EVALUATION OF ACUTE ESOPHAGEAL RADIATION-INDUCED DAMAGE USING MAGNETIC RESONANCE IMAGING: A FEASIBILITY STUDY IN MICE

Evaluation of acute esophageal radiation-induced damage using magnetic resonance imaging: a feasibility study in mice

Abstract Background Thoracic and head and neck cancer radiation therapy (RT) can cause damage to nearby healthy organs such as the esophagus, causing acute radiation-induced esophageal damage (ARIED).A non-invasive method to detect and monitor ARIED can facilitate optimizing RT to avoid ARIED while improving local tumor control.Current clinical gui

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Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction.

Interferon regulatory factor 8 (IRF8), also known as interferon consensus sequence-binding protein (ICSBP), is a transcription factor of the IRF family.IRF8 plays a key role in normal B cell differentiation, a cellular process that is intrinsically associated with Epstein-Barr virus (EBV) reactivation.However, whether IRF8 regulates EBV lytic repli

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